*Indicates Corresponding Author

Publications at University of Minnesota (Independent Career)

16. Expanding Native Mass Spectrometry to the Masses

Harvey SR*, Gadkari VV*, Ruotolo BT, Russell DH, Wysocki VH, Zhou M. J. Am. Soc. Mass Spectrom.. 2024 Feb 1


Publications from Michigan & Ohio State 

15. Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers

Makey D, Gadkari VV, Kennedy RT, Ruotolo BT.* Submitted for Peer Review. 2024

ChemRxiv: 10.26434/chemrxiv-2024-4j998

14. Collision Induced Unfolding Reveals Disease-Associated Stability Shifts in Mitochondrial tRNAs

Anders AG, Tidwell E, Gadkari VV, Koutmos M, Ruotolo BT.* J. Am. Chem. Soc. 2024 Feb 8


13. Performance Evaluation of In-source Ion Activation Hardware for Collision-Induced Unfolding of Proteins and Protein Complexes on a Drift Tube Ion Mobility-Mass Spectrometer

Gadkari VV, Juliano BR, Mallis CS, May JC, Kurulugama RT, Fjeldsted JC, McLean JA, Russell DH, Ruotolo BT.* Analyst. 2023 Dec 13; 148, 391-401. 


12. Mass Spectrometry Methods for Measuring Protein Stability

Vallejo DD, Rojas Ramírez C, Parson KF, Han Y, Gadkari VV, Ruotolo BT.* Chem. Rev.. 2022 Apr 27;122(8):7690-7719. 

doi: 10.1021/acs.chemrev.1c00857

11. Biochemical characterization of the interaction between KRAS and Argonaute 2

Waninger JJ, Beyett TS, Gadkari VV, Siebenaler RF, Kenum C, Shankar S, Ruotolo BT, Chinnaiyan AM, Tesmer JJG.* Biochem. Biophys. Rep.. 2021 Dec 20;29:101191. 

doi: 10.1016/j.bbrep.2021.101191

10. Mechanism of the small ATP-independent chaperone Spy is substrate specific

Mitra R, Gadkari VV, Meinen BA, van Mierlo CPM, Ruotolo BT, Bardwell JCA.* Nat. Commun.. 2021 Feb 8;12(1):851.

 doi: 10.1038/s41467-021-21120-8

9. Enhanced Collision Induced Unfolding and Electron Capture Dissociation of Native-like Protein Ions

Gadkari VV, Rojas Ramirez C, Vallejo DD, Kurulugama RT, Fjeldsted JC, Ruotolo BT.* Anal. Chem.. 2020 Dec 1;92(23):15489-15496. 

doi: 10.1021/acs.analchem.0c03372

8. Pervasive Charge Solvation Permeates Native-like Protein Ions and Dramatically Influences Top-down Sequencing Data

Polasky DA, Dixit SM, Keating MF, Gadkari VV, Andrews PC, Ruotolo BT.* J. Am. Chem. Soc.. 2020 Apr 8;142(14):6750-6760. 

doi: 10.1021/jacs.0c01076

7. SERF engages in a fuzzy complex that accelerates primary nucleation of amyloid proteins

Meinen BA, Gadkari VV, Stull F, Ruotolo BT, Bardwell JCA.* Proc. Natl. Acad. Sci. U.S.A.. 2019 Nov 12;116(46):23040-23049. 

doi: 10.1073/pnas.1913316116

6. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling

Gadkari VV, Harvey SR, Raper AT, Chu WT, Wang J, Wysocki VH, Suo Z.* Nucleic Acids Res. 2018 Apr 6;46(6):3103-3118. 

doi: 10.1093/nar/gky125

5. Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases

Raper AT , Reed AJ, Gadkari VV, Suo Z.* Chem. Res. Toxicol.. 2017 Jan 17;30(1):260-269. 

doi: 10.1021/acs.chemrestox.6b00342

4. Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases

Tokarsky EJ, Gadkari VV, Zahurancik WJ, Malik CK, Basu AK, Suo Z.* DNA Repair. 2016 Oct;46:20-28. 

doi: 10.1016/j.dnarep.2016.08.002

3. Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase

Raper AT, Gadkari VV, Maxwell BA, Suo Z.* Biochemistry. 2016 Apr 12;55(14):2187-96. 

doi: 10.1021/acs.biochem.6b00166 (PDF

2. Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase

Gadkari VV, Tokarsky EJ, Malik CK, Basu AK, Suo Z.* DNA Repair. 2014 Sep;21:65-77. 

doi: 10.1016/j.dnarep.2014.06.003 (PDF)

1. Mutagenic potential of 8-oxo-7, 8-dihydro-2′-deoxyguanosine bypass catalyzed by human Y-family DNA polymerases

Taggart DJ, Fredrickson SW, Gadkari VV, Suo Z.* Chem. Res. Toxicol.. 2014 May 19;27(5):931-40. 

doi: 10.1021/tx500088e.  (PDF)