Publications

*Indicates Corresponding Author

Publications at University of Minnesota (Independent Career)

2. Recent advances in gas phase unfolding: Instrumentation and applications

Matney R., Gadkari VV*. J Mass Spectrom. 2024;59(7):e5059.

1. Expanding Native Mass Spectrometry to the Masses

Harvey SR*, Gadkari VV*, Ruotolo BT, Russell DH, Wysocki VH, Zhou M. J. Am. Soc. Mass Spectrom.. 2024 Feb 1; 35(3), 646-652.

doi: https://doi.org/10.1021/jasms.3c00352

Publications from Michigan & Ohio State

16. Molecular insights into the interaction between a disordered protein and a folded RNA

Mitra R, Usher ET, Dedeoglu S, Crotteau MJ, Fraser, OA, Yennawar NH, Gadkari VV, Ruotolo BT, Holehouse AS, Salmon L, Showalter SA, Bardwell JCA bioRxiv. 2024. Submitted for peer-review

doi: https://doi.org/10.1101/2024.06.12.598678

15. Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers

Makey D, Gadkari VV, Kennedy RT, Ruotolo BT.* Anal. Chem. 2024 Apr 1; 96(15), 6021-6029.

doi: https://doi.org/10.1021/acs.analchem.4c00477

14. Collision Induced Unfolding Reveals Disease-Associated Stability Shifts in Mitochondrial tRNAs

Anders AG, Tidwell E, Gadkari VV, Koutmos M, Ruotolo BT.* J. Am. Chem. Soc. 2024 Feb 8; 146(7), 4412-4420.

doi: https://doi.org/10.1021/jacs.3c09230

13. Performance Evaluation of In-source Ion Activation Hardware for Collision-Induced Unfolding of Proteins and Protein Complexes on a Drift Tube Ion Mobility-Mass Spectrometer

Gadkari VV, Juliano BR, Mallis CS, May JC, Kurulugama RT, Fjeldsted JC, McLean JA, Russell DH, Ruotolo BT.* Analyst. 2023 Dec 13; 148, 391-401.

doi: https://doi.org/10.1039/D2AN01452A

12. Mass Spectrometry Methods for Measuring Protein Stability

Vallejo DD, Rojas Ramírez C, Parson KF, Han Y, Gadkari VV, Ruotolo BT.* Chem. Rev.. 2022 Apr 27;122(8):7690-7719.

doi: https://doi.org/10.1021/acs.chemrev.1c00857

11. Biochemical characterization of the interaction between KRAS and Argonaute 2

Waninger JJ, Beyett TS, Gadkari VV, Siebenaler RF, Kenum C, Shankar S, Ruotolo BT, Chinnaiyan AM, Tesmer JJG.* Biochem. Biophys. Rep.. 2021 Dec 20;29:101191.

doi: https://doi.org/10.1016/j.bbrep.2021.101191

10. Mechanism of the small ATP-independent chaperone Spy is substrate specific

Mitra R, Gadkari VV, Meinen BA, van Mierlo CPM, Ruotolo BT, Bardwell JCA.* Nat. Commun.. 2021 Feb 8;12(1):851.

doi: https://doi.org/10.1038/s41467-021-21120-8

9. Enhanced Collision Induced Unfolding and Electron Capture Dissociation of Native-like Protein Ions

Gadkari VV, Rojas Ramirez C, Vallejo DD, Kurulugama RT, Fjeldsted JC, Ruotolo BT.* Anal. Chem.. 2020 Dec 1;92(23):15489-15496.

doi: https://doi.org/10.1021/acs.analchem.0c03372

8. Pervasive Charge Solvation Permeates Native-like Protein Ions and Dramatically Influences Top-down Sequencing Data

Polasky DA, Dixit SM, Keating MF, Gadkari VV, Andrews PC, Ruotolo BT.* J. Am. Chem. Soc.. 2020 Apr 8;142(14):6750-6760.

doi: https://doi.org/10.1021/jacs.0c01076

7. SERF engages in a fuzzy complex that accelerates primary nucleation of amyloid proteins

Meinen BA, Gadkari VV, Stull F, Ruotolo BT, Bardwell JCA.* Proc. Natl. Acad. Sci. U.S.A.. 2019 Nov 12;116(46):23040-23049.

doi: https://doi.org/10.1073/pnas.1913316116

6. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling

Gadkari VV, Harvey SR, Raper AT, Chu WT, Wang J, Wysocki VH, Suo Z.* Nucleic Acids Res. 2018 Apr 6;46(6):3103-3118.

doi: https://doi.org/10.1093/nar/gky125

5. Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases

Raper AT , Reed AJ, Gadkari VV, Suo Z.* Chem. Res. Toxicol.. 2017 Jan 17;30(1):260-269.

doi: https://doi.org/10.1021/acs.chemrestox.6b00342

4. Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases

Tokarsky EJ, Gadkari VV, Zahurancik WJ, Malik CK, Basu AK, Suo Z.* DNA Repair. 2016 Oct;46:20-28.

doi: https://doi.org/10.1016/j.dnarep.2016.08.002

3. Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase

Raper AT, Gadkari VV, Maxwell BA, Suo Z.* Biochemistry. 2016 Apr 12;55(14):2187-96.

doi: https://doi.org/10.1021/acs.biochem.6b00166

2. Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase

Gadkari VV, Tokarsky EJ, Malik CK, Basu AK, Suo Z.* DNA Repair. 2014 Sep;21:65-77.

doi: https://doi.org/10.1016/j.dnarep.2014.06.003

1. Mutagenic potential of 8-oxo-7, 8-dihydro-2′-deoxyguanosine bypass catalyzed by human Y-family DNA polymerases

Taggart DJ, Fredrickson SW, Gadkari VV, Suo Z.* Chem. Res. Toxicol.. 2014 May 19;27(5):931-40.

doi: https://doi.org/10.1021/tx500088e