*Indicates Corresponding Author
Publications at University of Minnesota (Independent Career)
4. Surface Induced Unfolding Reveals Unique Structural Features and Enhances Machine Learning Classification Models
Matney R., Blake G., Gadkari V.V.*. Anal. Chem., 2025.
3. Structural insights into binding-site access and ligand recognition by human ABCB1
Kurre D., Dang P.X., Le, L.T.M., Gadkari V.V., Alam A.* EMBO J., 2025
2. Recent advances in gas phase unfolding: Instrumentation and applications
Matney R., Gadkari VV*. J Mass Spectrom., 2024;59(7):e5059.
1. Expanding Native Mass Spectrometry to the Masses
Harvey SR*, Gadkari VV*, Ruotolo BT, Russell DH, Wysocki VH, Zhou M. J. Am. Soc. Mass Spectrom.. 2024 Feb 1; 35(3), 646-652.
Mentored Publications from Michigan & Ohio State
16. Molecular insights into the interaction between a disordered protein and a folded RNA
Mitra R, Usher ET, Dedeoglu S, Crotteau MJ, Fraser, OA, Yennawar NH, Gadkari VV, Ruotolo BT, Holehouse AS, Salmon L, Showalter SA, Bardwell JCA. Proc Natl Acad Sci U S A. 2024.
15. Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers
Makey D, Gadkari VV, Kennedy RT, Ruotolo BT.* Anal. Chem. 2024 Apr 1; 96(15), 6021-6029.
14. Collision Induced Unfolding Reveals Disease-Associated Stability Shifts in Mitochondrial tRNAs
Anders AG, Tidwell E, Gadkari VV, Koutmos M, Ruotolo BT.* J. Am. Chem. Soc. 2024 Feb 8; 146(7), 4412-4420.
13. Performance Evaluation of In-source Ion Activation Hardware for Collision-Induced Unfolding of Proteins and Protein Complexes on a Drift Tube Ion Mobility-Mass Spectrometer
Gadkari VV, Juliano BR, Mallis CS, May JC, Kurulugama RT, Fjeldsted JC, McLean JA, Russell DH, Ruotolo BT.* Analyst. 2023 Dec 13; 148, 391-401.
12. Mass Spectrometry Methods for Measuring Protein Stability
Vallejo DD, Rojas Ramírez C, Parson KF, Han Y, Gadkari VV, Ruotolo BT.* Chem. Rev.. 2022 Apr 27;122(8):7690-7719.
11. Biochemical characterization of the interaction between KRAS and Argonaute 2
Waninger JJ, Beyett TS, Gadkari VV, Siebenaler RF, Kenum C, Shankar S, Ruotolo BT, Chinnaiyan AM, Tesmer JJG.* Biochem. Biophys. Rep.. 2021 Dec 20;29:101191.
10. Mechanism of the small ATP-independent chaperone Spy is substrate specific
Mitra R, Gadkari VV, Meinen BA, van Mierlo CPM, Ruotolo BT, Bardwell JCA.* Nat. Commun.. 2021 Feb 8;12(1):851.
9. Enhanced Collision Induced Unfolding and Electron Capture Dissociation of Native-like Protein Ions
Gadkari VV, Rojas Ramirez C, Vallejo DD, Kurulugama RT, Fjeldsted JC, Ruotolo BT.* Anal. Chem.. 2020 Dec 1;92(23):15489-15496.
8. Pervasive Charge Solvation Permeates Native-like Protein Ions and Dramatically Influences Top-down Sequencing Data
Polasky DA, Dixit SM, Keating MF, Gadkari VV, Andrews PC, Ruotolo BT.* J. Am. Chem. Soc.. 2020 Apr 8;142(14):6750-6760.
7. SERF engages in a fuzzy complex that accelerates primary nucleation of amyloid proteins
Meinen BA, Gadkari VV, Stull F, Ruotolo BT, Bardwell JCA.* Proc. Natl. Acad. Sci. U.S.A.. 2019 Nov 12;116(46):23040-23049.
6. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling
Gadkari VV, Harvey SR, Raper AT, Chu WT, Wang J, Wysocki VH, Suo Z.* Nucleic Acids Res. 2018 Apr 6;46(6):3103-3118.
5. Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases
Raper AT , Reed AJ, Gadkari VV, Suo Z.* Chem. Res. Toxicol.. 2017 Jan 17;30(1):260-269.
4. Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases
Tokarsky EJ, Gadkari VV, Zahurancik WJ, Malik CK, Basu AK, Suo Z.* DNA Repair. 2016 Oct;46:20-28.
3. Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase
Raper AT, Gadkari VV, Maxwell BA, Suo Z.* Biochemistry. 2016 Apr 12;55(14):2187-96.
2. Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase
Gadkari VV, Tokarsky EJ, Malik CK, Basu AK, Suo Z.* DNA Repair. 2014 Sep;21:65-77.
1. Mutagenic potential of 8-oxo-7, 8-dihydro-2′-deoxyguanosine bypass catalyzed by human Y-family DNA polymerases
Taggart DJ, Fredrickson SW, Gadkari VV, Suo Z.* Chem. Res. Toxicol.. 2014 May 19;27(5):931-40.